Running shown to keep dementia at bay as you age

Cardiovascular memory  W=Researchers at UT Southwestern noted a 47 percent increase in blood flow to regions associated with memory. Whether you work out in a group or by yourself, movement is necessary. Reams of research detail the importance of regular exercise. Besides physical health, staying fit leads to good mental health. A year-long study at UT Southwestern again confirms this fact. Published in The Journal of Alzheimer's Disease, 30 volunteers (median age: 66) either ran or stretched for 25-30 minutes three times a week. Each participant had no recent experience with exercise. Every volunteer showed some sign of memory impairment, which was a requirement, as this was a study on memory. After a year of continuous exercise, researchers measured cerebral blood flow in each participant. The aerobic group showed increased blood flow to two regions key to memory retention: the anterior cingulate cortex (responsible for attention allocation, reward anticipation, impulse control, and more) and the prefrontal cortex (decision making, personality, planning complex behavior, and more). While the stretching group experienced minimal improvement in memory tests over the course of the year, the aerobic group saw a 47 percent jump in test scores. As lead author of the study, Binu Thomas, a postdoctoral research fellow in the Center for BrainHealth at UT Southwestern Medical Center, says, aerobic exercise works in your favor at any age. Noting the study was only a small group, he continues, "Cerebral blood flow is a part of the puzzle, and we need to continue piecing it together. But we've seen enough data to know that starting a fitness program can have lifelong benefits for our brains as well as our hearts." Copyright © 2020 Big Think, All rights reserved. You've received the Big Think Weekly Newsletter because you, or someone on your behalf, registered you at http://www.bigthink.com. Big Think, 18 E 17th St 5th Fl, New York NY 10003 You can unsubscribe any time.

New study connects cardiovascular exercise with improved memory

Researchers at UT Southwestern noted a 47 percent increase in blood flow to regions associated with memory.

DEREK BERES

29 May, 2020

An elderly man runs during his morning exercises at the promenade on the Bund along the Huangpu Rive the Bund in Shanghai on May 18, 2017.

Photo: Johannes Eisele/AFP via Getty Images

• Researchers at UT Southwestern observed a stark improvement in memory after cardiovascular exercise.
• The year-long study included 30 seniors who all had some form of memory impairment.
• The group of seniors that only stretched for a year did not fair as well in memory tests.

When sheltering at home began in Los Angeles, a crew of ambitious Angelenos didn't let gym closures stop their workouts. #100miles30days spread to over 400 participants around the world. It didn't matter how you split up the distance; you just had to walk or run 100 miles in April. While a lot of fitness culture hashtags rely on gimmickry, this challenge was social media at its best.
Exercise is always important, especially during a time when isolation negatively impacts mental health. Initiatives like the above keep individuals motivated while the term "community" temporarily loses meaning. A workout partner or group fitness class holds you accountable. Some people need responsibility to keep moving, even if one as simple as a hashtag.
Whether you work out in a group or by yourself, movement is necessary. Reams of research detail the importance of regular exercise. Besides physical health, staying fit leads to good mental health. A year-long study at UT Southwestern again confirms this fact.
Published in The Journal of Alzheimer's Disease, 30 volunteers (median age: 66) either ran or stretched for 25-30 minutes three times a week. Each participant had no recent experience with exercise. Every volunteer showed some sign of memory impairment, which was a requirement, as this was a study on memory.
The stretch group performed a series of flexibility and balance exercises designed to keep their heart rate stable while strengthening their upper and lower bodies. The cardiovascular group completed a number of heart-raising exercises. After a year of continuous exercise, researchers measured cerebral blood flow in each participant.

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The aerobic group showed increased blood flow to two regions key to memory retention: the anterior cingulate cortex (responsible for attention allocation, reward anticipation, impulse control, and more) and the prefrontal cortex (decision making, personality, planning complex behavior, and more). While the stretching group experienced minimal improvement in memory tests over the course of the year, the aerobic group saw a 47 percent jump in test scores.

Lithuania's Austra Reinberga (C) runs next to New Zealand's Marcia Petley (L) and Columbia's Maria Pastora Londono (R) during the women's 100m final for athletes between 85 and 89 years old, during the World Masters Athletics Championships on August 7, 2015 in Lyon, southeastern France.Photo: Philippe Desmazes/AFP via Getty ImagesAs lead author of the study, Binu Thomas, a postdoctoral research fellow in the Center for BrainHealth at UT Southwestern Medical Center, says, aerobic exercise works in your favor at any age. Noting the study was only a small group, he continues,

"Cerebral blood flow is a part of the puzzle, and we need to continue piecing it together. But we've seen enough data to know that starting a fitness program can have lifelong benefits for our brains as well as our hearts."

This study follows a wealth of data detailing the impact of exercise on cognition. A University of Vermont study suggests mental health patients consider exercise before starting prescription medication, going so far as to recommend medical centers build gyms in a new therapeutic model.
A prior review of 33 studies advocated weightlifting as an important protocol for curbing depression. Another study based in Amsterdam called exercise an ideal intervention for treating anxiety disorders and depression. Oxford and Yale researchers discovered the same.
In 2013, the RAND Corporation estimated that diseases of dementia cost America between $157 billion to $215 billion annually. Previous research specifically cites cardiovascular exercise as key for fighting dementia, including this 2010 study and this study from 2017. In 2013, epidemiologist Bryan James told NPR that aging does not have to result in memory loss.

"It's simply not pre-destined for all human beings. Lots of people live into their 90s and even 100s with no symptoms of dementia."

While Thomas speculates that a drug could target blood flow in the regions cited in his study, perhaps we should consider what's kept us healthy for hundreds of thousands of years: regular movement. Your body is in the shape you train for, so best to train it well. Your brain will thank you.
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Stay in touch with Derek on Twitter, Facebook and Substack. His next book is "Hero's Dose: The Case For Psychedelics in Ritual and Therapy."

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alzheimer's brain health medical research mental health Memory